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Toward a “structural BLAST”: Using structural relationships to infer function

We outline a set of strategies to infer protein function from structure. The overall approach depends on extensive use of homology modeling, the exploitation of a wide range of global and local geometric relationships between protein structures and the use of machine learning techniques. The combina...

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Autori principali: Dey, Fabian, Cliff Zhang, Qiangfeng, Petrey, Donald, Honig, Barry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610042/
https://ncbi.nlm.nih.gov/pubmed/23349097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2225
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