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Toward a “structural BLAST”: Using structural relationships to infer function
We outline a set of strategies to infer protein function from structure. The overall approach depends on extensive use of homology modeling, the exploitation of a wide range of global and local geometric relationships between protein structures and the use of machine learning techniques. The combina...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley Subscription Services, Inc., A Wiley Company
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610042/ https://ncbi.nlm.nih.gov/pubmed/23349097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2225 |
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