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Structural relationships among proteins with different global topologies and their implications for function annotation strategies

It has become increasingly apparent that geometric relationships often exist between regions of two proteins that have quite different global topologies or folds. In this article, we examine whether such relationships can be used to infer a functional connection between the two proteins in question....

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Detalhes bibliográficos
Main Authors: Petrey, Donald, Fischer, Markus, Honig, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765090/
https://ncbi.nlm.nih.gov/pubmed/19805138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907971106
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