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Atoh1 induces auditory hair cell recovery in mice after ototoxic injury

OBJECTIVES: To evaluate the ability of the Ad28.gfap.atoh1 to promote hair cell regeneration and hearing recovery in cochlea injured with kanamycin and furosemide. STUDY DESIGN: In vivo model of hair cell ablation and subsequent treatment with Atoh1 METHODS: The hair cells of C57BL/6 mice were ablat...

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Hlavní autoři: Kraft, Shannon, Hsu, Chi, Brough, Douglas E., Staecker, Hinrich
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609898/
https://ncbi.nlm.nih.gov/pubmed/23483451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.22171
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