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Optimizing atoh1 induced vestibular hair cell regeneration

OBJECTIVES/HYPOTHESIS: Determine the optimal design characteristics of an adenoviral vector to deliver atoh1 and induce regeneration of vestibular hair cells. STUDY DESIGN: Evaluation of a mouse model of intra-labyrinthine gene delivery. Tissue culture of mouse and human macular organs. METHODS: Mac...

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Detalhes bibliográficos
Publicado no:Laryngoscope
Main Authors: Staecker, Hinrich, Schlecker, Christina, Kraft, Shannon, Praetorius, Mark, Hsu, Chi, Brough, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267505/
https://ncbi.nlm.nih.gov/pubmed/24938696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.24775
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