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Nuclear localization signals in phage terminal proteins provide a novel gene delivery tool in mammalian cells

Terminal proteins (TPs) of bacteriophages prime DNA replication and become covalently linked to the genome ends. Unexpectedly, we have found functional eukaryotic nuclear localization signals (NLSs) within the TP sequences of bacteriophages from diverse families and hosts. Given the role of bacterio...

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書誌詳細
主要な著者: Redrejo-Rodríguez, Modesto, Muñoz-Espín, Daniel, Holguera, Isabel, Mencía, Mario, Salas, Margarita
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609834/
https://ncbi.nlm.nih.gov/pubmed/23750294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.22829
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