Sex Determining Region Y-Box 2 (SOX2) Amplification Is an Independent Indicator of Disease Recurrence in Sinonasal Cancer

OBJECTIVES: The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells. Recently, amplification of the SOX2 gene locus has been described in squamous cell carcinoma (SCC) of different organ site...

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Main Authors: Schröck, Andreas, Göke, Friederike, Wagner, Patrick, Bode, Maike, Franzen, Alina, Braun, Martin, Huss, Sebastian, Agaimy, Abbas, Ihrler, Stephan, Menon, Ropika, Kirsten, Robert, Kristiansen, Glen, Bootz, Friedrich, Lengerke, Claudia, Perner, Sven
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609820/
https://ncbi.nlm.nih.gov/pubmed/23544055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059201
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