Curcumin Inhibits Transforming Growth Factor-β1-Induced EMT via PPARγ Pathway, Not Smad Pathway in Renal Tubular Epithelial Cells

Tubulointerstitial fibrosis (TIF) is the final common pathway in the end-stage renal disease. Epithelial-to-mesenchymal transition (EMT) is considered a major contributor to the TIF by increasing the number of myofibroblasts. Curcumin, a polyphenolic compound derived from rhizomes of Curcuma, has be...

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Detalhes bibliográficos
Main Authors: Li, Rui, Wang, Yunman, Liu, Yujun, Chen, Qijing, Fu, Wencheng, Wang, Hao, Cai, Hui, Peng, Wen, Zhang, Xuemei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609782/
https://ncbi.nlm.nih.gov/pubmed/23544048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058848
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