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Chito-Oligosaccharide Inhibits the De-Methylation of a ‘CpG’ Island within the Leptin (LEP) Promoter during Adipogenesis of 3T3-L1 Cells

Chito-oligosaccharide (COS) is a natural bioactive compound, which has been shown to suppress lipid metabolic genes and lipid accumulation in differentiating adipocytes. Leptin has been identified as a key regulator of energy homeostasis and is known to be under epigenetic regulation during adipogen...

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Detalhes bibliográficos
Main Authors: Bahar, Bojlul, O’Doherty, John V., O’Doherty, Alan M., Sweeney, Torres
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609775/
https://ncbi.nlm.nih.gov/pubmed/23544120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060011
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