Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

In skeletal muscle, the actin cytoskeleton-regulating GTPase, Rac1, is necessary for insulin-dependent GLUT4 translocation. Muscle contraction increases glucose transport and represents an alternative signaling pathway to insulin. Whether Rac1 is activated by muscle contraction and regulates contrac...

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Autori principali: Sylow, Lykke, Jensen, Thomas E., Kleinert, Maximilian, Mouatt, Joshua R., Maarbjerg, Stine J., Jeppesen, Jacob, Prats, Clara, Chiu, Tim T., Boguslavsky, Shlomit, Klip, Amira, Schjerling, Peter, Richter, Erik A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609592/
https://ncbi.nlm.nih.gov/pubmed/23274900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0491
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