Amyloid-β Induces Hepatic Insulin Resistance In Vivo via JAK2

Amyloid-β (Aβ), a natural product of cell metabolism, plays a key role in the pathogenesis of Alzheimer’s disease (AD). Epidemiological studies indicate patients with AD have an increased risk of developing type 2 diabetes mellitus (T2DM). Aβ can induce insulin resistance in cultured hepatocytes by...

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Detalhes bibliográficos
Main Authors: Zhang, Yi, Zhou, Ben, Deng, Bo, Zhang, Fang, Wu, Jingxia, Wang, Yuangao, Le, Yingying, Zhai, Qiwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609589/
https://ncbi.nlm.nih.gov/pubmed/23223021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0670
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