Enhanced Absorption of Insulin Aspart as the Result of a Dispersed Injection Strategy Tested in a Randomized Trial in Type 1 Diabetic Patients

OBJECTIVE: We investigated the impact of two different injection strategies on the pharmacokinetics and pharmacodynamics of insulin aspart in vivo in an open-label, two-period crossover study and verified changes in the surface-to-volume ratio ex vivo. RESEARCH DESIGN AND METHODS: Before the clinica...

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Bibliographic Details
Main Authors: Mader, Julia K., Birngruber, Thomas, Korsatko, Stefan, Deller, Sigrid, Köhler, Gerd, Boysen, Susanne, Augustin, Thomas, Mautner, Selma I., Sinner, Frank, Pieber, Thomas R.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609526/
https://ncbi.nlm.nih.gov/pubmed/23193211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-1319
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