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Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide

PURPOSE: Fast-acting insulin aspart (faster aspart) is a novel formulation of insulin aspart containing two additional excipients: niacinamide, to increase early absorption, and L-arginine, to optimize stability. The aim of this study was to evaluate the impact of niacinamide on insulin aspart absor...

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Vydáno v:Pharm Res
Hlavní autoři: Kildegaard, Jonas, Buckley, Stephen T., Nielsen, Rasmus H., Povlsen, Gro K., Seested, Torben, Ribel, Ulla, Olsen, Helle B., Ludvigsen, Svend, Jeppesen, Claus B., Refsgaard, Hanne H. F., Bendtsen, Kristian M., Kristensen, Niels R., Hostrup, Susanne, Sturis, Jeppe
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373292/
https://ncbi.nlm.nih.gov/pubmed/30746556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2578-7
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