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Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide

PURPOSE: Fast-acting insulin aspart (faster aspart) is a novel formulation of insulin aspart containing two additional excipients: niacinamide, to increase early absorption, and L-arginine, to optimize stability. The aim of this study was to evaluate the impact of niacinamide on insulin aspart absor...

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Bibliografische gegevens
Gepubliceerd in:Pharm Res
Hoofdauteurs: Kildegaard, Jonas, Buckley, Stephen T., Nielsen, Rasmus H., Povlsen, Gro K., Seested, Torben, Ribel, Ulla, Olsen, Helle B., Ludvigsen, Svend, Jeppesen, Claus B., Refsgaard, Hanne H. F., Bendtsen, Kristian M., Kristensen, Niels R., Hostrup, Susanne, Sturis, Jeppe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373292/
https://ncbi.nlm.nih.gov/pubmed/30746556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2578-7
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