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TRPV4 Dysfunction Promotes Renal Cystogenesis in Autosomal Recessive Polycystic Kidney Disease

The molecular mechanism of cyst formation and expansion in autosomal recessive polycystic kidney disease (ARPKD) is poorly understood, but impaired mechanosensitivity to tubular flow and dysfunctional calcium signaling are important contributors. The activity of the mechanosensitive Ca(2+)-permeable...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zaika, Oleg, Mamenko, Mykola, Berrout, Jonathan, Boukelmoune, Nabila, O'Neil, Roger G., Pochynyuk, Oleh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609133/
https://ncbi.nlm.nih.gov/pubmed/23411787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050442
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