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Function of Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) as a Mechanical Transducer in Flow-sensitive Segments of Renal Collecting Duct System

The TRPV4 Ca(2+)-permeable channel is sensitive to mechanical stimuli. In the current study we have employed immunocytochemical staining in kidney slices and functional assessments (Ca(2+) imaging) in isolated, split-opened, tubule segments to define TRPV4 sites of expression and flow-dependent func...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Berrout, Jonathan, Jin, Min, Mamenko, Mykola, Zaika, Oleg, Pochynyuk, Oleh, O'Neil, Roger G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308780/
https://ncbi.nlm.nih.gov/pubmed/22298783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308411
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