Llwytho...

Cis phosphorylated tau as the earliest detectable pathogenic conformation in Alzheimer disease, offering novel diagnostic and therapeutic strategies

After protein phosphorylation on certain serine or threonine residues preceding a proline (pSer/Thr-Pro), the function of certain phosphorylated protein is further regulated by cis-trans conformational change. Due to the lack of any tool to detect such two conformations in cells, however, it is not...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nakamura, Kazuhiro, Zhou, Xiao Zhen, Lu, Kun Ping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609116/
https://ncbi.nlm.nih.gov/pubmed/23154634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22849
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