Učitavanje...

The Earliest Tau Dysfunction in Alzheimer's Disease?: Tau Phosphorylated at S422 as a Toxic Seed

In this Commentary, Voss and colleagues discuss the work of Vana et al. who show that tau phosphorlyated at S422 in the cholinergic basal forebrain is the earliest marker of tau pathogenesis. The ramifications of these findings for future drug development specifically for tauopathies and Alzheimer&#...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Voss, Kellen, Koren, John, Dickey, Chad A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204013/
https://ncbi.nlm.nih.gov/pubmed/21964186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.020
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!