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The neurodegeneration in Alzheimer disease and the prion protein

The concept of “prion-like” has been proposed to explain the pathogenic mechanism of the principal neurodegenerative disorders associated with protein misfolding, including Alzheimer disease (AD). Other evidence relates prion protein with AD: the cellular prion protein (PrP(C)) binds β amyloid oligo...

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Detalhes bibliográficos
Main Authors: Forloni, Gianluigi, Sclip, Alessandra, Borsello, Tiziana, Balducci, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609052/
https://ncbi.nlm.nih.gov/pubmed/23324596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23286
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