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Alzheimer disease: A tale of two prions

Alzheimer disease (AD) has traditionally been thought to involve the misfolding and aggregation of two different factors that contribute in parallel to pathogenesis: amyloid-β (Aβ) peptides, which represent proteolytic fragments of the transmembrane amyloid precursor protein, and tau, which normally...

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Detalhes bibliográficos
Main Authors: Nussbaum, Justin M., Seward, Matthew E., Bloom, George S.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609044/
https://ncbi.nlm.nih.gov/pubmed/22965142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22118
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