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Detection and characterization of classical and “uncommon” exon 19 Epidermal Growth Factor Receptor mutations in lung cancer by pyrosequencing

BACKGROUND: The management of advanced stage non-small cell lung cancer is increasingly based on diagnostic and predictive analyses performed mostly on limited amounts of tumor tissue. The evaluation of Epidermal Growth Factor Receptor (EGFR) mutations have emerged as the strongest predictor of resp...

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Bibliografiska uppgifter
Huvudupphovsmän: Righi, Luisella, Cuccurullo, Alessandra, Vatrano, Simona, Cappia, Susanna, Giachino, Daniela, Giuli, Paolo De, Ardine, Mara, Novello, Silvia, Volante, Marco, Scagliotti, Giorgio V, Papotti, Mauro
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608975/
https://ncbi.nlm.nih.gov/pubmed/23497146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-114
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