Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE(2) dependent pathway

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are one of the major components of the immune-suppressive network, play key roles in tumor progression and limit therapeutic responses. Recently, we reported that tumor spheres formed by breast cancer cell lines were visibly smaller in a Th(1) enr...

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Bibliografski detalji
Glavni autori: Thakur, Archana, Schalk, Dana, Tomaszewski, Elyse, Kondadasula, Sri Vidya, Yano, Hiroshi, Sarkar, Fazlul H, Lum, Lawrence G
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608954/
https://ncbi.nlm.nih.gov/pubmed/23394575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-35
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