Luminescence-based in vivo monitoring of NF-κB activity through a gene delivery approach

BACKGROUND: Monitoring activity of specific signaling pathways in vivo is challenging and requires highly sensitive methods to detect dynamic perturbations in whole organisms. RESULTS: In vivo gene delivery of a luciferase reporter followed by bioluminiscence imaging allows measuring NF-κB activity...

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Bibliographic Details
Main Authors: Osorio, Fernando G, de la Rosa, Jorge, Freije, José MP
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Methodology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608945/
https://ncbi.nlm.nih.gov/pubmed/23517552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-19
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