New Modulators for IGF-I Activity within IGF-I Processing Products

Insulin-like growth factor I (IGF-I) is a key regulator of muscle development and growth. The pre-pro-peptide produced by the Igf1 gene undergoes several post-translational processing steps to result in a secreted mature protein, which is thought to be the obligate ligand for the IGF-I receptor (IGF...

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Bibliographic Details
Main Authors: Brisson, Becky K., Barton, Elisabeth R.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608916/
https://ncbi.nlm.nih.gov/pubmed/23543904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00042
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