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Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity

Our research proved that chemical character of the C-5 substituent significantly determines the antibacterial activity of the Mannich bases derived from 4,5-disubstituted 1,2,4-triazole-3-thiones. This activity was considerably increased by an introduction of a chlorine atom to the phenyl ring. The...

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Hlavní autoři: Plech, Tomasz, Wujec, Monika, Majewska, Magdalena, Kosikowska, Urszula, Malm, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608860/
https://ncbi.nlm.nih.gov/pubmed/23543889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-012-0248-y
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