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Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids
We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids. A number of these compounds displayed enhanced activity against Gram-positive and Gram-negative bacteria when compared to c...
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| Vydáno v: | Molecules |
|---|---|
| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272816/ https://ncbi.nlm.nih.gov/pubmed/25859782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20046254 |
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