Highly conserved upstream regions of the alpha 1-antitrypsin gene in two mouse species govern liver-specific expression by different mechanisms.

alpha 1-Antitrypsin (AT), the major elastase inhibitor in mammalian serum, is produced primarily in the liver. We have characterized AT gene structure and expression in the mouse species Mus caroli, which expresses high levels of AT in the kidneys as well as in the liver. Analysis of cDNA and genomi...

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Udgivet i:Mol Cell Biol
Main Authors: Latimer, J J, Berger, F G, Baumann, H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1689000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.760
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