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A Common Mode of Recognition for Methylated CpG

Much is known about vertebrate DNA methylation, however it is not known how methylated CpG within particular sequences is recognized. Two recent structures of C2H2 zinc finger (ZnF) proteins, in complex with methylated DNA, reveal a common recognition mode for 5-methylcytosine (5mC) that involves a...

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Sonraí Bibleagrafaíochta
Main Authors: Liu, Yiwei, Zhang, Xing, Blumenthal, Robert M., Cheng, Xiaodong
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608759/
https://ncbi.nlm.nih.gov/pubmed/23352388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2012.12.005
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