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Requirement for Dicer in Survival of Proliferating Thymocytes Experiencing DNA Double Strand Breaks

The Dicer nuclease generates small RNAs that regulate diverse biological processes through post-transcriptional gene repression and epigenetic silencing of transcription and recombination. Dicer-deficient cells exhibit impaired differentiation, activity, proliferation, and survival. Dicer inactivati...

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Bibliografiske detaljer
Main Authors: Brady, Brenna L., Rupp, Levi J., Bassing, Craig H.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608727/
https://ncbi.nlm.nih.gov/pubmed/23427252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200957
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