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Orai1 Function is Essential for T Cell Homing to Lymph Nodes
In T lymphocytes, Ca(2+) release-activated Ca(2+) (CRAC) channels composed of Orai1 subunits trigger antigen-induced gene expression and cell proliferation through the NFAT pathway. We evaluated the requirement of CRAC channel function for lymphocyte homing using expression of a dominant-negative Or...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608704/ https://ncbi.nlm.nih.gov/pubmed/23455504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202212 |
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