Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance

BACKGROUND & AIMS: Heme oxygenase-1 (HO-1) and its metabolic by-product, carbon monoxide (CO), protect against intestinal inflammation in experimental models of colitis, but little is known about their intestinal immune mechanisms. We investigated the interactions among CO, HO-1, and the enteric...

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Hlavní autoři: Onyiah, Joseph C., Sheikh, Shehzad Z., Maharshak, Nitsan, Steinbach, Erin C., Russo, Steven M., Kobayashi, Taku, Mackey, Lantz C., Hansen, Jonathan J., Moeser, Adam J., Rawls, John F., Borst, Luke B., Otterbein, Leo E., Plevy, Scott E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608700/
https://ncbi.nlm.nih.gov/pubmed/23266559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.12.025
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