Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance

BACKGROUND & AIMS: Heme oxygenase-1 (HO-1) and its metabolic by-product, carbon monoxide (CO), protect against intestinal inflammation in experimental models of colitis, but little is known about their intestinal immune mechanisms. We investigated the interactions among CO, HO-1, and the enteric...

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Main Authors: Onyiah, Joseph C., Sheikh, Shehzad Z., Maharshak, Nitsan, Steinbach, Erin C., Russo, Steven M., Kobayashi, Taku, Mackey, Lantz C., Hansen, Jonathan J., Moeser, Adam J., Rawls, John F., Borst, Luke B., Otterbein, Leo E., Plevy, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608700/
https://ncbi.nlm.nih.gov/pubmed/23266559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.12.025
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