Development of Strategies for SNP Detection in RNA-Seq Data: Application to Lymphoblastoid Cell Lines and Evaluation Using 1000 Genomes Data

Next-generation RNA sequencing (RNA-seq) maps and analyzes transcriptomes and generates data on sequence variation in expressed genes. There are few reported studies on analysis strategies to maximize the yield of quality RNA-seq SNP data. We evaluated the performance of different SNP-calling method...

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Detalhes bibliográficos
Main Authors: Quinn, Emma M., Cormican, Paul, Kenny, Elaine M., Hill, Matthew, Anney, Richard, Gill, Michael, Corvin, Aiden P., Morris, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608647/
https://ncbi.nlm.nih.gov/pubmed/23555596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058815
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