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Multiplex Target Enrichment Using DNA Indexing for Ultra-High Throughput SNP Detection

Screening large numbers of target regions in multiple DNA samples for sequence variation is an important application of next-generation sequencing but an efficient method to enrich the samples in parallel has yet to be reported. We describe an advanced method that combines DNA samples using indexes...

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Detalhes bibliográficos
Main Authors: Kenny, Elaine M., Cormican, Paul, Gilks, William P., Gates, Amy S., O'Dushlaine, Colm T., Pinto, Carlos, Corvin, Aiden P., Gill, Michael, Morris, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041504/
https://ncbi.nlm.nih.gov/pubmed/21163834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsq029
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