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Platelets Recognize Brain-Specific Glycolipid Structures, Respond to Neurovascular Damage and Promote Neuroinflammation

Platelets respond to vascular damage and contribute to inflammation, but their role in the neurodegenerative diseases is unknown. We found that the systemic administration of brain lipid rafts induced a massive platelet activation and degranulation resulting in a life-threatening anaphylactic-like r...

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Detalhes bibliográficos
Main Authors: Sotnikov, Ilya, Veremeyko, Tatyana, Starossom, Sarah C., Barteneva, Natalia, Weiner, Howard L., Ponomarev, Eugene D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608633/
https://ncbi.nlm.nih.gov/pubmed/23555611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058979
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