Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca(2+)-ATPase (PfSERCA or PfATP6) has...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Miao, Miao, Wang, Zenglei, Yang, Zhaoqing, Yuan, Lili, Parker, Daniel M., Putaporntip, Chaturong, Jongwutiwes, Somchai, Xangsayarath, Phonepadith, Pongvongsa, Tiengkham, Moji, Hazuhiko, Dinh Tuong, Trinh, Abe, Tomoko, Nakazawa, Shusuke, Kyaw, Myat Phone, Yan, Guiyun, Sirichaisinthop, Jeeraphat, Sattabongkot, Jetsumon, Mu, Jianbing, Su, Xin-zhuan, Kaneko, Osamu, Cui, Liwang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608609/
https://ncbi.nlm.nih.gov/pubmed/23555629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059192
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