JAK2 V617F Genotype Is a Strong Determinant of Blast Transformation in Primary Myelofibrosis

PURPOSE: The influence of JAK2 V617F mutation on blast transformation (BT) and overall survival (OS) in primary myelofibrosis (PMF) is controversial. In a large cohort of patients we applied competing risks analysis for studying the influence of JAK2V617F mutation on BT in PMF. PATIENTS AND METHODS:...

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Autores principales: Barosi, Giovanni, Poletto, Valentina, Massa, Margherita, Campanelli, Rita, Villani, Laura, Bonetti, Elisa, Viarengo, Gianluca, Catarsi, Paolo, Klersy, Catherine, Rosti, Vittorio
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608564/
https://ncbi.nlm.nih.gov/pubmed/23555782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059791
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