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A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory

The interaction of nuclear pore proteins (Nups) with active genes can promote their transcription. In yeast, some inducible genes interact with the nuclear pore complex both when active and for several generations after being repressed, a phenomenon called epigenetic transcriptional memory. This int...

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Main Authors: Light, William H., Freaney, Jonathan, Sood, Varun, Thompson, Abbey, D'Urso, Agustina, Horvath, Curt M., Brickner, Jason H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608542/
https://ncbi.nlm.nih.gov/pubmed/23555195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001524
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