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Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory

In yeast and humans, previous experiences can lead to epigenetic transcriptional memory: repressed genes that exhibit mitotically heritable changes in chromatin structure and promoter recruitment of poised RNA polymerase II preinitiation complex (RNAPII PIC), which enhances future reactivation. Here...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: D'Urso, Agustina, Takahashi, Yoh-hei, Xiong, Bin, Marone, Jessica, Coukos, Robert, Randise-Hinchliff, Carlo, Wang, Ji-Ping, Shilatifard, Ali, Brickner, Jason H
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951200/
https://ncbi.nlm.nih.gov/pubmed/27336723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16691
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