Ovariectomy Induces a Shift in Fuel Availability and Metabolism in the Hippocampus of the Female Transgenic Model of Familial Alzheimer's

Previously, we demonstrated that reproductive senescence in female triple transgenic Alzheimer's (3×TgAD) mice was paralleled by a shift towards a ketogenic profile with a concomitant decline in mitochondrial activity in brain, suggesting a potential association between ovarian hormone loss and...

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Autors principals: Ding, Fan, Yao, Jia, Zhao, Liqin, Mao, Zisu, Chen, Shuhua, Brinton, Roberta Diaz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608536/
https://ncbi.nlm.nih.gov/pubmed/23555795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059825
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