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Three amino acid changes in PB1-F2 of highly pathogenic H5N1 avian influenza virus affect pathogenicity in mallard ducks

Despite reports that the PB1-F2 protein contributes to influenza virus pathogenicity in the mouse model, little is known about its significance in avian hosts. In our previous study the A/Vietnam/1203/04 (H5N1) wild-type virus (wtVN1203) was more lethal to mallard ducks than a reverse genetics (rg)–...

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Bibliografski detalji
Glavni autori: Marjuki, Henju, Scholtissek, Christoph, Franks, John, Negovetich, Nicholas J., Aldridge, Jerry R., Salomon, Rachelle, Finkelstein, David, Webster, Robert G.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608463/
https://ncbi.nlm.nih.gov/pubmed/20383540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-010-0666-4
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