Molecular Changes in the Polymerase Genes (PA and PB1) Associated with High Pathogenicity of H5N1 Influenza Virus in Mallard Ducks

The highly pathogenic (HP) influenza viruses H5 and H7 are usually nonpathogenic in mallard ducks. However, the currently circulating HP H5N1 viruses acquired a different phenotype and are able to cause mortality in mallards. To establish the molecular basis of this phenotype, we cloned the human A/...

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Autori principali: Hulse-Post, D. J., Franks, J., Boyd, K., Salomon, R., Hoffmann, E., Yen, H. L., Webby, R. J., Walker, D., Nguyen, T. D., Webster, R. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951362/
https://ncbi.nlm.nih.gov/pubmed/17553873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00435-07
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