Molecular Changes in the Polymerase Genes (PA and PB1) Associated with High Pathogenicity of H5N1 Influenza Virus in Mallard Ducks

The highly pathogenic (HP) influenza viruses H5 and H7 are usually nonpathogenic in mallard ducks. However, the currently circulating HP H5N1 viruses acquired a different phenotype and are able to cause mortality in mallards. To establish the molecular basis of this phenotype, we cloned the human A/...

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Autors principals: Hulse-Post, D. J., Franks, J., Boyd, K., Salomon, R., Hoffmann, E., Yen, H. L., Webby, R. J., Walker, D., Nguyen, T. D., Webster, R. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951362/
https://ncbi.nlm.nih.gov/pubmed/17553873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00435-07
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