RNA-Sequencing Quantification of Hepatic Ontogeny and Tissue Distribution of mRNAs of Phase II Enzymes in Mice

Phase II conjugating enzymes play key roles in the metabolism of xenobiotics. In the present study, RNA sequencing was used to elucidate hepatic ontogeny and tissue distribution of mRNA expression of all major known Phase II enzymes, including enzymes involved in glucuronidation, sulfation, glutathi...

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Bibliografiske detaljer
Main Authors: Lu, Hong, Gunewardena, Sumedha, Cui, Julia Y., Yoo, Byunggil, Zhong, Xiao-bo, Klaassen, Curtis D.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608454/
https://ncbi.nlm.nih.gov/pubmed/23382457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.050211
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