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Impaired Function of Prejunctional Adenosine A(1) Receptors Expressed by Perivascular Sympathetic Nerves in DOCA-Salt Hypertensive Rats

Increased sympathetic nervous system activity contributes to deoxycorticosterone acetate (DOCA)-salt hypertension in rats. ATP and norepinephrine (NE) are coreleased from perivascular sympathetic nerves. NE acts at prejunctional α(2)-adrenergic receptors (α(2)ARs) to inhibit NE release, and α(2)AR f...

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Detalhes bibliográficos
Main Authors: Sangsiri, Sutheera, Dong, Hua, Swain, Gregory M., Galligan, James J., Xu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608448/
https://ncbi.nlm.nih.gov/pubmed/23397055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.199612
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