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Novel and Distinct Metabolites Identified Following a Single Oral Dose of α- or γ-Hexabromocyclododecane in Mice

The metabolism of α- and γ-hexabromocyclododecane (HBCD) was investigated in adult C57BL/6 female mice. α- or γ-[(14)C]HBCD (3 mg/kg bw) was orally administered with subsequent urine and feces collection for 4 consecutive days; a separate group of mice were dosed and sacrificed 3 hours post-exposure...

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Bibliographic Details
Main Authors: Hakk, Heldur, Szabo, David T., Huwe, Janice, Diliberto, Janet, Birnbaum, Linda S.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608416/
https://ncbi.nlm.nih.gov/pubmed/23171393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/es303209g
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