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Development and validation of ultra-performance liquid chromatographic method with tandem mass spectrometry for determination of lenalidomide in rabbit and human plasma

BACKGROUND: Lenalidomide (LND) is a potent novel thalidomide analog which demonstrated remarkable clinical activity in treatment of multiple myeloma disease via a multiple-pathways mechanism. Validated sensitive method with high throughput is required for the determination of lenalidomide for pharma...

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Detalhes bibliográficos
Main Authors: Iqbal, Muzaffar, Wani, Tanveer A, Khalil, Nasr Y, Darwish, Ibrahim A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608328/
https://ncbi.nlm.nih.gov/pubmed/23316845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-7-7
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