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Low doses of cocaine decrease, and high doses increase, anxiety-like behavior and brain progestogen levels among intact rats

There are sex and hormonal differences in response to cocaine that have been demonstrated in people and animal models. Cocaine can alter secretion of progestogens, such as progesterone (P), and its neuroactive metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP). However, little research has been done on...

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Autors principals: Kohtz, Amy S., Paris, Jason J., Frye, Cheryl A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608214/
https://ncbi.nlm.nih.gov/pubmed/20171966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2010.02.005
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