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Progesterone reduces depressive behavior of young ovariectomized, aged progestin receptor knockout, and aged wild type mice in the tail suspension test
Progestins may have effects to reduce depressive behavior, in part through actions of its metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP) at GABA(A) receptors, rather than through intracellular progestin receptors. In this study, we examined the effects of progesterone (10 mg/kg, subcutaneous inject...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608207/ https://ncbi.nlm.nih.gov/pubmed/19965943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881109349836 |
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