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Progesterone reduces depressive behavior of young ovariectomized, aged progestin receptor knockout, and aged wild type mice in the tail suspension test

Progestins may have effects to reduce depressive behavior, in part through actions of its metabolite, 5α-pregnan-3α-ol-20-one (3α,5α-THP) at GABA(A) receptors, rather than through intracellular progestin receptors. In this study, we examined the effects of progesterone (10 mg/kg, subcutaneous inject...

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Autore principale: Frye, Cheryl A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608207/
https://ncbi.nlm.nih.gov/pubmed/19965943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881109349836
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