Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation.

The human insulinlike growth factor I receptor was overexpressed in NIH 3T3 cells as well as human and rat primary fibroblast strains. The NIH 3T3 cells displayed a ligand-dependent, highly transformed phenotype. When exposed to insulinlike growth factor I or supraphysiologic levels of insulin, NIH...

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Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Kaleko, M, Rutter, W J, Miller, A D
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 1990
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.2.464-473.1990
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