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Isotope pattern deconvolution for peptide mass spectrometry by non-negative least squares/least absolute deviation template matching

BACKGROUND: The robust identification of isotope patterns originating from peptides being analyzed through mass spectrometry (MS) is often significantly hampered by noise artifacts and the interference of overlapping patterns arising e.g. from post-translational modifications. As the classification...

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Detalhes bibliográficos
Main Authors: Slawski, Martin, Hussong, Rene, Tholey, Andreas, Jakoby, Thomas, Gregorius, Barbara, Hildebrandt, Andreas, Hein, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608065/
https://ncbi.nlm.nih.gov/pubmed/23137144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-291
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